Whether you need to enrich your analytes, remove matrix components,
or lower detection limits for trace-level water analysis,
the highly modular design of the Agilent 1200 Infinity Series Online SPE solutions
provide you with the flexibility to tailor your system to match virtually any analytical LC challenge.
Agilent's online SPE solutions are based on the 1290 Infinity Flexible Cube
that houses up to two valves and re-usable SPE cartridges.
Valve heads are easy to mount on the drives thanks to Agilent's Quick-Change valve technology.
The Flexible Cube also has a built-in piston pump and
a solvent selection valve for conditioning and loading the cartridges.
Combined with Agilent's 6400 Series triple quadrupole mass spectrometers
this online SPE solution takes you into a new dimension of ultra low level detection
with straightforward, turn-key operation.
An extensive portfolio of valves makes it easy to customize your online SPE system to fit your needs.
Combine these kits with the SPE starter set for applications such as:
Direct injection
Multi-SPE
High volume injection, or Flask sampling
The starter set opens the door to endless online SPE possibilities with a 2-position/10-port valve
mounted in the Flexible Cube and connected to two SPE cartridges.
The Flexible Cube's built-in piston pump and solvent selection valve
allow you to condition the first cartridge with up to three different solvents.
In parallel, the second cartridge is in the analytical flow path.
After injection, the piston pump is used to deliver up to 1.8 milliliters of sample onto the SPE cartridge
to enrich the analytes of interest while the matrix constituents such as salt are flushed to waste.
When the sample has been loaded, the 2-position/10-port valve switches to the "elute" position
and the LC pump extracts the enriched analytes from the SPE cartridge
for separation on the analytical column and detection with the triple quadrupole mass spectrometer.
Expand your application possibilities further by adding the Direct Injection Kit to your SPE Starter Set.
This kit includes an additional 2-position/10-port valve so that your system can now
alternate between online SPE and direct injection onto the analytical column.
This configuration gives you the flexibility to run calibration standards or check system performance
in direct injection mode - without the SPE cartridge in the flow path,
and without the need to change plumbing or valves, or even switch to a different LC/MS system.
Switching the additional valve takes you back to online SPE mode.
You can now inject your sample and enrich the analytes of interest on the SPE cartridge,
and flush the matrix constituents to waste.
When the sample has been loaded, the valve is switched to the "elute" position
and the enriched analytes are extracted for separation on the analytical column
and detection with the triple quadrupole mass spectrometer.
Agilent 1200 Infinity Series Online SPE solutions boost productivity of your laboratory
by saving time and reducing costs.
While advanced valve solutions give you the utmost automation flexibility
to address even the most challenging applications,
Agilent's triple quadrupole mass spectrometers deliver unmatched sensitivity and quantitative performance.
Flexible Online SPE is just one of a wave of innovative technologies to ensure your
Agilent LC and LC/MS solutions stay at the forefront of separation potential.