Agilent Technologies 2100 Bioanalyzer - 2100 Expert Software B.02.08 (SR2)

August 30, 2012

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Table of Contents
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1.  Introduction

2.  What's New ?
    2.15 2100 Expert Software B.02.08 (SR2)
    2.14 2100 Expert Software B.02.08 (SR1)
    2.13 2100 Expert Software B.02.08
    2.12 2100 Expert Software B.02.07 (Patch 01)
    2.11 2100 Expert Software B.02.07
    2.10 2100 Expert Software B.02.06 (Patch 01) 
    2.9  2100 Expert Software B.02.06 
    2.8  2100 Expert Software B.02.05 
    2.7  2100 Expert Software B.02.04 
    2.6  2100 Expert Software B.02.03 
    2.5  2100 Expert Software B.02.02 
    2.4  2100 Expert Software B.02.01 
    2.3  2100 Expert Software B.01.03 
    2.2  2100 Expert Software B.01.02 
    2.1  2100 Expert Software B.01.01 - Initial Release

3.  System Configuration
    3.1  System Requirements
    3.1.1  PC Hardware Requirements
    3.1.2  Operating System Requirements
3.2  Instrument Requirements
3.3  Software Configuration
3.4  USB to Serial Adapter

4.  Getting Help
  4.1  Using Online Help
  4.2  Online Help with Security Pack
  4.3  Getting Support

5.  Software Installation and Setup
5.1	Installation Instructions
5.2	Registration
5.3  Setting up the Security Pack
5.4  Setting up the Security Pack with domain users
5.5  Uninstall Instructions
5.6	Secured Area Migration from B.02.01 to B.02.02
5.7	Secured Area Migration from B.02.02/B.02.03 to B.02.04 or later
5.8	Downgrade Instructions

6.  Known Problems or Limitations

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1.  Introduction
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This document provides last minute information about the Agilent 2100 Bioanalyzer - 2100 Expert Software. 

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2.  What's New ?
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2.15 2100 Expert Software B.02.08 (SR2)

  NOTE!
  This software version requires firmware revision C.01.069

  General Enhancements
    Fixed audit trail inconsistency when working with “Save Selected Sample” in
    Security Pack 
        
    Prior versions of Security Pack (B.02.03 to B.02.08 (SR1)) were discovered to possibly display incorrect sample names when the “Save Selected Sample” option is chosen. This does not apply to any data files where no selected samples have been saved into a new file. A fix has been implemented with B.02.08 (SR2).
	For any entries in the audit trail affecting deselected samples using “Save Selected Sample” the sample names will be displayed as ‘Deselected’.  

2.14 2100 Expert Software B.02.08 (SR1)

	NOTE!
	This software version requires firmware revision C.01.069

General Enhancements
 
•	Fixed instrument connection issues causing the data acquisition to abort intermittently
•	Fixed a bug causing rRNA ratio result to change to 0 after modifying fragment start or end times
•	Fixed IQ and OQ issues with Operating Systems languages other than US English
•	Fixed instrument detection issues on systems with unusual COM port names
	
Please note:
This software version has been tested with the newest version of the Prolific USB to Serial Adapter driver (v1.4.17). If you are using a USB to Serial Adapter driver to connect your computer to the 2100 Bioanalyzer, please make sure to uninstall all previous versions of this driver and install the version which is delivered with this CD (please see chapter 3.4 for more details).

2.13 2100 Expert Software B.02.08

	NOTE!
	This software version requires firmware revision C.01.069

General Enhancements
 
•	Added support of Windows 7 Professional (32 bit and 64 bit)
•	New export format: AIA/ANDI 

2.12 2100 Expert Software B.02.07 (Patch 01)

	NOTE!
	This software version requires firmware revision C.01.069

General Enhancements
 
•	Fixed a bug when performing HV accuracy test
•	Added missing help index
•	Fixed a bug causing system freeze when trying to search help

2.11 2100 Expert Software B.02.07

	NOTE!
	This software version requires firmware revision C.01.069

General Enhancements
 
•	Support for new Plant RNA Nano and Plant RNA Pico assay
(run assays with standard RNA 6000 nano or RNA 6000 pico kits and reagents)
•	Support for new High Sensitivity DNA assay
•	Support of Windows Vista Business SP1

Please note:
Starting with this software version it is not possible to operate 2100 Bioanalyzer instruments with product number G2938A.
Last software version to support G2938A is Agilent 2100 Expert Software B.02.06.
G2938B, G2938C and G2939A type instruments can be used without any problems.
Existing data files acquired by G2938A can be reanalyzed without any problems.

In case you already installed B.02.07 and you still want to use your existing G2938A instrument, you have the following options:

1. Having no data acquired yet by B.02.07, downgrade software (see section 5.8).
2. Having data acquired already by B.02.07 with another instrument, downgrade software and install B.02.07 (or higher) on a separate PC.

2.10 2100 Expert Software B.02.06 (Patch 01)

	NOTE!
	This software version requires firmware revision C.01.069

General Enhancements
 
•	Fixed a bug when opening DNA files and Protein 80 and 230 files that have been created with a version prior to B.02.06
(DNA: corrected concentration calculation, Protein: improved upper marker detection)

2.9 2100 Expert Software B.02.06

	NOTE!
	This software version requires firmware revision C.01.069

General Enhancements
 
·	Support for new High Sensitivity Protein 250 assay
•	Optional input of sample names prior to run
•	Support for RS232/USB adapter (PN 8121-1013)
•	Ability to preview the gel-like image in the Microsoft Windows Explorer (Thumbnails view)

2.8 2100 Expert Software B.02.05

General Enhancements
 
·	Updated Small RNA Series II assay kit guide
·	Aligned quantitation for Small RNA Series II assay 

Please note:
This software version contains only changes relevant for the Small RNA Series II assay compared to 2100 Expert B.02.04.

2.7 2100 Expert Software B.02.04

General Enhancements
 
·	Support for new Small RNA Series II assay
•	Improved Protein Series II assays

Security Pack
 
·	Seamless Migration from older versions (see section 5.7)

2.6 2100 Expert Software B.02.03
NOTE!
This software version requires firmware revision C.01.055

General Enhancements
 
·	Reporting of result tables based on user settings
·	New Series II Assays included
·	Improved Setpoint Explorer with color coding of changed set points
·	Improved comparison context to support display of up to 48 samples per file
·	Added Analysis Engine Checks for Series II assays in the Verification Context

Security Pack
 
·	Support of Domain users
·	Result table layout can be defined per method for reporting 
·	Automated migration option from B.02.02 to B.02.03 during setup

2.5 2100 Expert Software B.02.02
General Enhancements
 
·	Added support for the new Agilent 2100 Electrophoresis Bioanalyzer instrument (G2939A).

Software Maintenance

Repair of a fault described in Service Note 2100-31.
Differences were observed in data visualization and generated results between results at the end of a chip run and following reprocessing of the same data file.
•	Repair of a fault which sporadically occurred when a file was closed in Data Context via context menu in files tree view during chip run.
Repair of a fault related to Security Pack Export/Import functionality.
When a file was exported or imported to the Secured Area, a new file version was generated but neither the signature log nor the audit trail was showing any entry for the new file version.

2.4 2100 Expert Software B.02.01
NOTE!
This software version requires firmware revision C.01.050

General Enhancements
 
·	Added support for 21 CFR Part 11 requirements (Security Pack license required)
·	Added RNA Integrity number (RIN) calculation for Eukaryote Total RNA assays
·	Support of XML as native data format
•	Improved reporting capabilities
•	Enhanced Result Flagging Forms 
•	Various improvements in different areas
 
2.3 2100 Expert Software B.01.03
The Agilent 2100 Expert Software has been amended by fixes.
It includes a tool for objectively assessing RNA integrity.

2.2 2100 Expert Software B.01.02
The Agilent 2100 Expert Software has been amended by fixes.

2.1 2100 Expert Software B.01.01
The new Agilent 2100 Expert Software is the first element of Agilent's plan to further develop the Agilent 2100 Bioanalyzer system into a compliant solution for customers in regulated environments, such as involved in the QA/QC and manufacturing of antibodies and other protein pharmaceuticals, as well as DNA- and RNA-based drugs. 
As part of this introduction, Agilent is providing software support for installation qualification (IQ) and operational qualification/performance validation (OQ/PV) in a dedicated validation context. Agilent is also introducing IQ and OQ/PV services for all B-type and later instruments as well as "Declarations of Conformity" for reagents and chips. Declarations of Conformity state that during final verification, a product's functional characteristics are individually tested for conformance with the manufacturer's internal specifications.
Agilent next plans to introduce a security software pack, which will enable full 21 CFR Part 11 compliance, supporting-requirements such as electronic signatures, audit trails and user authentication.
The 2100 Expert Software also provides a consolidated platform for all Agilent 2100 Bioanalyzer assays i.e. DNA, RNA, protein and cell analysis. Previously, two dedicated software modules were required for these types of analysis (Bio Sizing and Cell Fluorescence). 

Additional software enhancements include:
•	improved integrator and manual integration capabilities; 
•	normal and advanced user modes; 
•	color-coded result flagging tool for electrophoresis assays; 
•	enhanced reporting, export and printing functions; 
•	customizable result tables and gel-like images;
•	new and improved assays.

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3.  System Configuration
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3.1 System Requirements

The Agilent 2100 Expert Software is supported on specific bundle configurations.
•	HPQ desktop (EVO D530 SFF or newer)
•	HPQ laptop (NC6320 or newer)

3.1.1 PC Hardware (minimum requirements)

	Processor:		Pentium 4 with 3 GHz or Core 2 Duo with 1.8 GHz
	Memory:		1024 MByte
	Ports:		1-2 serial ports or one free USB port
	Display:		Resolution of 1280 x 1024 pixels 
	Hard disk:		20 GByte

Desktop configurations are supported with one or two instruments per PC. Laptop configurations are supported only with one Bioanalyzer connected.

3.1.2 Operating System requirements

The Agilent 2100 Expert Software has been tested to run on 
•	Microsoft © Windows XP SP3 with English (US) language settings
•	Microsoft © Windows 7 Professional 64 bit with English (US) language settings

3.2 Instrument Requirements

•	Agilent 2100 Bioanalyzer running the corresponding firmware (see note below) required for proper operation of the Agilent 2100 Bioanalyzer - 2100 Expert Software

NOTE!
Software version B.02.08 requires firmware revision C.01.069
Software version B.02.07 requires firmware revision C.01.069
Software version B.02.06 requires firmware revision C.01.069
Software version B.02.05 requires firmware revision C.01.055
Software version B.02.04 requires firmware revision C.01.055
Software version B.02.03 requires firmware revision C.01.055
Software version B.02.02 requires firmware revision C.01.050
Software version B.02.01 requires firmware revision C.01.050
Software version B.01.03 requires firmware revision C.01.048
Software version B.01.02 requires firmware revision C.01.048 (*)

* (with upgrade to Series II Assays firmware revision C.01.053 is required and installed.)

3.3 Software Configuration

•	Screen Savers
Screen savers should not be used together with Agilent 2100 Bioanalyzer - 2100 Expert Software. Screen savers can cause undue loading of the CPU that may result in the loss of data from the instrument during data collection periods.

•	Advanced Power Management (APM, ACPI)
Advanced power management features of the PC BIOS must be disabled for systems that are connected to the Agilent 2100 Bioanalyzer. See the Installation Manual of your PC for more details.

•	Any Energy Star compliant PC should have the Energy Save features disabled to prevent the loss of data during data collection periods. Problems may also be exhibited by I/O error with the instruments. I/O errors will result in the loss of data. They can be found in the system logbook.

•	Regional Options
Regional options must be set to English (Unites States).

•	Microsoft Office Findfast
The MS Office FindFast tool has shown some negative impact on the data acquisition from the instrument if it happens to run simultaneously with a chip run. It needs to be disabled to guarantee that no data loss or interruption will occur.

•	Display Defaults on Windows 
The default configuration for control of the display monitor is to "Show window contents while dragging". With this setting, the window is continually redrawn as a window panel is moved. For windows that have very complex graphics in them (such as a chromatogram with many peaks) the system can become so busy redrawing the window that it cannot process any other input. For example, a user might drag a graphics window to a new location with the mouse and see the window continue to move even after the mouse is no longer moving.

If this problem occurs on your system, you can change the control to draw only the outline of the window as it is moved instead of the full window. To change the setting under Windows XP, go to the "Start" button and select the "Control Panel". When the Control Panel is displayed, double click on "Display". In the Display control, select the "Appearance" tab. On that screen, click on the "Effects…" button. In the following form, make sure that "Show window content while dragging" is unchecked. The windows movement will now be much quicker, and there will not be a problem with the window continuing to move after the mouse has come to a stop.

•	Large Fonts
If your display is setup to display information using large fonts some of the information on the screen may be hidden or obscured. Please use small fonts to make sure all information is properly displayed.

•	Regional options must be set to English (United States) 

•	Certain anti-virus SW and anti-spy-ware SW have negatively impacted the performance of the 2100 Expert SW. Communication of the 2100 Expert to the 2100 Bioanalyzer might be disturbed and can lead to failed hardware diagnosis or stopped data acquisition. Please consider carefully to shut down anti-virus SW and anti-spy-ware SW while data are acquired by the 2100 Bioanalyzer.

3.4 USB to Serial Adapter
On all Agilent Technologies 2100 Bioanalyzer Laptop systems (G2943CA) and 2100 Expert SW Laptop bundles (G2953CA) (e.g. HP  ProBook 6560b, Status as of October 2012) a driver needed to operate the supplied USB-to-Serial adapter comes pre-installed.

Start working with your system after the following steps:
1. Physically connect the 2100 Bioanalyzer and the laptop by using the USB-to-Serial adapter cable and the standard Serial RS-232 cable.
2. Turn on the 2100 Bioanalyzer and the laptop.
3. The 2100 Expert SW must be opened and the correct COM port must be selected in the Instrument Context.

For third party computers without a serial port the use of the Agilent USB-to-Serial adapter (Part-No.: 8121-1013) is an option to control an Agilent 2100 Bioanalyzer. Only the above specified adapter in combination with a given driver is supported. The USB-to-Serial adapter cable includes a Prolific PL-2303HX controller component, which requires the installation of a driver. It needs to be connected via an USB port of the PC and emulates a serial port.

The driver can be found on this SW-CD in the following folder:
<CD-ROM>:\Support\Driver\8121-1013\PL2303_Prolific_DriverInstaller_v1417.exe

Install the driver prior to connecting the adapter and the 2100 Bioanalyzer and proceed as described below.
1. Close the 2100 Expert Software
2. Execute the installation program of the driver and follow the instructions. Reboot the operating system.
3. Physically connect the 2100 Bioanalyzer and the laptop by using the USB-to-Serial adapter cable and the standard Serial RS-232 cable.
4. Open 2100 Expert Software and select the correct, new COM port in the Instrument context.
 
The serial port and the assigned COM port number is also visible from the Microsoft Windows device manager. 

NOTE!
Please do NOT use the driver provided on a CD together with the cable delivery.
Instead use only the driver distributed on THIS 2100 Expert Software CD!

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4.  Getting Help
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4.1 Using Online Help

Agilent 2100 Bioanalyzer - 2100 Expert's online Help system is compatible with the Windows Help subsystems. The Agilent 2100 Bioanalyzer - 2100 Expert Help file contains all of the information you'll need to operate your Agilent 2100 Bioanalyzer.

To access the Online Help, select Help from the Agilent 2100 Bioanalyzer - 2100 Expert menu bar, then Contents and Index from the drop-down menu.

To acquire information about your screen mode and printer type, select System Info from the About screen.

4.2 Online Help with Security Pack

To access the Online Help under Security Pack, select Help from the Agilent 2100 Bioanalyzer - 2100 Expert menu bar, then Contents and Index from the drop-down menu.
Please note the online help under Security Pack differs from the standard 2100 Expert online help content. It contains additional help information about functions and features of the security pack. 

4.3 Getting Support

Agilent Technologies is committed to providing a reliable, high-quality product that is easy to use.
  
Documentation:
In your "Installation and Safety Manual" that comes with the instrument, you will find help on system installation and Agilent 2100 Bioanalyzer hardware specifications.
For more in depth Agilent 2100 Bioanalyzer system information, refer to the user guide on CD-ROM. You will also find a Troubleshooting chapter on the CD-ROM, dealing with hardware as well as application related problems and how to solve them.

Customer Support Team:
However, if you have any problem installing or using the Agilent 2100 Bioanalyzer, we want to know about it and help you.

Please contact your local Agilent Technologies Customer Care Center to get support on Agilent 2100 Bioanalyzer questions (for details please visit the following web page: www.agilent.com/genomics/contactus). 
Agilent Technologies also provides electronic support through the World Wide Web.

World Wide Web	:		
					www.agilent.com/genomics/bioanalyzer

In any communication with the Agilent 2100 Bioanalyzer support team regarding a problem with the Agilent 2100 Bioanalyzer system, please clearly state the following:

•	The product name and version number.

•	Your name, address, e-mail address and telephone number.

•	Your hardware and software configuration. Go to the Help->About dialog to get your diagnostic information.

•	The serial number of your instrument.

•	A description of the problem, and what you were trying to do when the problem occurred.

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5.  Software Installation and Setup
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5.1 Installation Instructions

The 2100 Expert installation program SETUP.EXE is a Microsoft Windows application. You must have Windows XP or Windows 7 installed prior to installing 2100 Expert Software. To install 2100 Expert, perform the following steps:

1.	Start Windows, if you haven't already done so.

2. Before installing please make sure you have the appropriate rights to install the software on your computer. You need to have an account with administrative rights to successfully install all needed components.  

3. Insert the CD with the Agilent 2100 Bioanalyzer - 2100 Expert Software Package into your CD ROM drive.

4. Close all running programs, including all instances of the Agilent 2100 Expert software.

4. From the Start menu, select run.  

5. In the dialog box, enter:
d:\setup.exe 
(you will need to change the drive letter and the path in the command line above to match your current location).

6. Click on the OK button.

7. Follow the instructions given by the setup wizard for correct installation of the product. 

8. If you are prompted to restart the PC after the setup, please use the same user account you used for the installation to log on to the PC after the reboot. This is necessary to guarantee the correct installation of the 2100 Expert Software. 

Low Disc Space: 
If the installation aborts because of low disc space, it is possible to install 2100 Expert with redirecting the temp directory to another hard-drive. This means that during installation the windows installer file will be extracted temporarily from the setup.exe file to the selected temp directory. After the installation the windows installer file will be deleted.

If you are using Windows XP, please perform the following steps:	
a)	From the Windows Explorer: Double click on RedirectTempDirSetup.vbs on this installation CD
b)	Select a drive and folder on another hard-disk (e.g. d:\temp) to redirect the temp directory during installation which provides enough free disk space (1 GByte).
c)	Click Ok.
d)	Please wait. Installation will start.

If you are using Windows 7, please perform the following steps:	
a)	Go to Control Panel -> System and Security
b)	Select “Change User Account Control settings” under “Action Center”
c)	Note down the current position of the slider before continuing. Then move the slider down to “never notify” (a reboot will be required after modification).
d)	From the Windows Explorer: Double click on RedirectTempDirSetup.vbs on this installation CD
e)	Select a drive and folder on another hard-disk (e.g. d:\temp) to redirect the temp directory during installation which provides enough free disk space (1 GByte).
f)	Click Ok.
g)	Please wait. Installation will start.
h)	After installation has finished: if you have disabled UAC in step c), go back to Control Panel -> System and Security and turn UAC on again by moving the slider on its initial position.

5.2. Registration

In order to connect to an instrument you need to add a license for that class of assays in the software and one to enable instrument control (regardless of how many instruments you want to control).
You can open the "License Administration Tool" via the menu item "Help/Registration...". 
In the dialog box navigate to the "Add License" tab, select "Agilent 2100 Bioanalyzer" as product. 
Then enter the instrument control license and one or both of electrophoresis or flow cytometry license certificates:

Always required:
- 2100 Instrument Ctrl license: 	xxxxxx - xxxxxxxx - xxxxxxx

Enter one or both:
- 2100 Electrophoresis license:	xxxxxx - xxxxxxxx - xxxxxxx

- 2100 Flow Cytometry license: 	xxxxxx - xxxxxxxx - xxxxxxx

After entering each certificate press "Add" to store it permanently.

In order to install the security pack you also need to install this license, which will trigger an additional set up process afterwards.

- 2100 Security Pack License: 	xxxxxx - xxxxxxxx - xxxxxxx

5.3  Setting up the Security Pack

After adding the security pack license the software will shut down and automatically launch another setup wizard after restart that will guide you through the setup of the security pack.
After the restart, please log on to the operating system using the same account that has been used to install the first part of the application.
This wizard will create a new local user account used internally by the application (2100System). In addition you need to specify the initial administrator account for the 2100 Expert Software with security pack. You can either create a new, local 2100 administrator (recommended) or select an existing user. All other users of the 2100 Expert Software can be defined later by the 2100 administrator in the application itself. Beside the users the setup wizard creates a new folder on your PC called "SecuredArea". This part of the file system will be locked for normal users of that system. Only 2100 Administrators or 2100 Backup operators are allowed to access this folder. The software will safe all created data in this folder and its sub folders.

After successful installation of the security pack you need to log on to the application in order to use it. For the 1st time you access the software please use the account you defined as initial 2100 administrator. No other user beside this will be able to start the application initially. Afterwards any user set up in the System Context as valid user of the 2100 Expert Software will be able to start the application.

5.4	How to setup security pack with domain users

Note:
Please contact your local Agilent representative if you want to upgrade your 2100 Expert Software with security pack from B.02.01 to B.02.04 or later.

Step-by-Step instruction:
•	Logon to the Windows OS using an account from the domain which has administrator rights for the PC

•	Determine or create a new domain account that shall act as 2100System user within your installation

•	Enter the license Keys as described in chapter 5.2

•	After restart of the application, please enter the domain\2100System user into the appropriate fields of the dialog. Use the ‘Browse…’ button to select the account being used as the generic 2100system account.

•	You can use any domain user account that fulfills the prerequisites described at the end of this chapter.
Enter the password of the selected account and press the <Next> button.

•	In the next dialog you are informed where the “SecuredArea” folder will be installed on your local PC.
Press <Next> to continue.

•	Now the migration process starts.
If you want to migrate your current users and their roles within 2100 Expert, your system wide settings and as well your method and data files to your new 2100 Expert Software version B.02.08 (SR2) then you should check the box besides “Migrate Security Pack” and select the location of the secured area folder backup.

•	In the final dialog of the setup wizard you should set up the initial 2100 administrator, who can initially log on the 2100 Expert application and will then be able to set up the remaining 2100 Expert users in their desired role for the application. 

You can either create a new local account for this task or also assign it to an existing domain account. Use the ‘Browse…’ button to select the account being used as the 2100 Administration account.

•	After the setup wizard has finished its tasks you can log on to the 2100 Expert application using the 2100 administrator account specified in the previous step.

!!! NOTE !!! NOTE !!! NOTE !!! NOTE !!! NOTE !!! NOTE !!!

Prerequisites for a domain 2100 System account:
If you want to setup the 2100 System account as a domain user it should fulfill the following prerequisites:
-	should be a default domain user
-	“User must change password at next logon” should be disabled
-	“Password never expires” should be enabled

Using domain network resources out of security pack
If you want to use network resources from the domain (e.g. network printers) out of the 2100 Expert application with Security pack installed then you have to set up these resources for the used 2100 system domain account on this PC.
E.g. if you want to use a specific network printer from within 2100 Expert with Security Pack installed, then logon to Windows with the 2100 System domain account specified during the setup of security pack. Add the network printer for this account and after successful installation of this printer, just log off from windows again. 
Logon to windows again using the usual domain user account. From this point in time you should be able to print from within 2100 Expert with Security pack to this network printer.

5.5  Uninstall Instructions

If after installing Agilent 2100 Bioanalyzer - 2100 Expert Software, you find it necessary to remove the software from your computer, perform the following steps:

Uninstall instructions for Windows 

1.	Run the Windows Control Panel

2.	Open the Add/Remove Programs applet from Control Panel.

3.	Select Agilent Technologies 2100 Bioanalyzer - 2100 Expert from the list of applications that can be uninstalled by Windows.

4.	Click on the Add/Remove button to uninstall Agilent 2100 Bioanalyzer - 2100 Expert Software.

5.	For complete security pack uninstallation: Click on the Add/Remove button to uninstall Agilent 2100 Bioanalyzer - 2100 Expert secured area. 

5.6	Secured Area Migration from B.02.01 to B.02.02

The migration of the Secured Area is currently a manual process. 
Please contact your local Agilent representative if you want to upgrade your 2100 Expert Software with security pack from B.02.01 to B.02.02.

ATTENTION! 
It is important that you do not try to perform the migration yourself, otherwise data loss might happen!

5.7	Secured Area Migration from B.02.08 to B.02.08 (SR2)

Note! 
As for all updates, it's a good idea to have an actual backup of your system and your data PRIOR to the migration.

When you start 2100 Expert after installation of the B.02.08 (SR2) version onto an existing B.02.08 version with security pack the following message box is shown.

In order to continue with 2100 Expert it is required to start the migration process by pressing ’Yes’ (‘No’ would stop the execution of 2100 Expert)

Now a new window is shown that indicates the progress of the migration.

If the migration process was successful, press ‘Close’ and 2100 Expert will start automatically.

It is recommended to choose the Agilent IQ-service or alternatively to run the build in Software-IQ in the verification context if this fulfills your internal software update policy.

5.8	Downgrade Instructions

Note! 
In case you already created data files with the newer version of the software (acquired new data or saved data files of previous versions after modification) you have to consider that those files cannot be opened with older versions of the software. In order to run the older and the newer version of the software in parallel, you need to install them onto separate PCs.

In order to return to a previous version of 2100 expert software, perform the following steps:

1. Make sure you have your license keys at hand (found at Help->About 2100 Expert...)
2. De-install the existing 2100 Expert Software revision
3. On demand reboot the system
4. Install the older 2100 Expert Software revision

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6.  Known Problems or Limitations
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For details please see accompanying Software Status Bulletin (Support\SSB\2100 Expert Software.html) on this Software CD-ROM or an updated online SSB under http://www.chem.agilent.com/en-US/Support/Downloads/Patches/Pages/default.aspx (here click on Lab-on-a-Chip). 
Please enter your instrument license /Instrument number to identify on the web-page.

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© Copyright 2003-2011 Agilent Technologies, Inc. Use, reproduction, and distribution are subject to approval of Agilent Technologies.

Microsoft, Windows, Windows XP, Windows Vista and Windows 7 are U.S. registered trademarks of Microsoft Corporation.

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